Vitamin B1
Also known as thiamine
Trade name
Thiamine Hydrochloride (Biological Therapies), Thiamine Sterop
Strength
50 mg/mL (volume: 2 mL)
100 mg/mL (volume: 1 mL)
IV administration
Give undiluted or dilute to 50 mg/mL or weaker and give over 30 minutes, preferably via a large peripheral vein.
Other routes of administration
IM: Thiamine Hydrochloride (Biological Therapies) only: Suitable. Give undiluted.
SC: Not recommended.
Compatible IV fluids
Vitamin B1 50 mg/mL or weaker:
Sodium chloride 0.9% is the preferred diluent.
Glucose 5%
Additional information
Extravasation risk.
Observe closely for anaphylactic reactions.
Use only when facilities for cardiac monitoring and cardio-respiratory resuscitation exist.
An intradermal diluted test dose may be required prior to administration in patients who have suspected sensitivity or a history of allergy. Refer to local guidelines for information.
Protect from light during storage.
Thiamine Hydrochloride (Biological Therapies): Caution in neonates; contains benzyl alcohol which has been linked with ‘gasping syndrome’.
Discard any unused vial contents.
Thiamine Sterop: Solution should be clear, colourless to slightly yellow.