Tigecycline

Trade name

Tigecycline (Juno), Tygacil 

Presentation and preparation

Vial size
(powder volume)
Fluid to add
Volume to add
Resulting concentration
50 mg
(negligible)
Sodium chloride 0.9% OR Glucose 5% 5.3 mL 10 mg/mL

Swirl gently to dissolve.

Vials contain a significant amount of overage; Tigecycline (Juno) and Tygacil 50 mg vials contain 53 mg tigecycline.

IV administration

Further dilute to 1 mg/mL or weaker and infuse over 30 minutes to 1 hour.

Other routes of administration

IM: Not recommended.

SC: Not recommended.

Compatible IV fluids

Glucose 5%

Sodium chloride 0.9%

Y-site only:

Hartmann's

Potassium chloride 20 mmol/L

Additional information

Observe closely for anaphylactic reactions. 

Reconstituted solution should be yellow to orange.

Use immediately after reconstitution.

Discard any unused vial contents.


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