Thiopental
Also known as thiopentone
Trade name
Omegapharm Thiopental
Presentation and preparation
|
Vial size
(powder volume) |
Fluid to add
|
Volume to add
|
Resulting concentration
|
|---|---|---|---|
| 470 mg (negligible) |
Water for injections | 9.4 mL | 50 mg/mL |
Reconstitute to 50 mg/mL for IV administration.
IV administration
Injection: Use undiluted, or dilute to 20 to 50 mg/mL, and give over at least 20 seconds.
Intermittent infusion: Dilute to 20 to 50 mg/mL and infuse over 10 minutes to 1 hour.
Continuous infusion: Dilute to 2 to 4 mg/mL and give as a continuous infusion.
Other routes of administration
IM: Not recommended.
SC: Not recommended.
Compatible IV fluids
Glucose 5%
Sodium chloride 0.9%
Y-site only:
Plasma-Lyte 148
Additional information
Extravasation risk.
For use in theatre or intensive care settings only.
Use only when facilities for cardiac monitoring and cardio-respiratory resuscitation exist.
May cause hypotension, decreased cardiac output and respiratory depression.
Discard any unused vial contents.
Flush line well after dose administration to avoid re-sedation during recovery.