Trade name
Prograf
Presentation and preparation
5 mg/mL (volume: 1 mL)
IV administration
Dilute to 4 – 100 microgram/mL and give as a continuous infusion over 24 hours.
May be given as a twice-daily dose over 2 or 4 hours depending on indication; refer to local protocols.
Non-PVC bags and giving sets should be used.
Other routes of administration
IM: Not recommended.
SC: Not recommended.
Compatible IV fluids
Glucose 5%
Sodium chloride 0.9%
Y-site only and sodium chloride 0.9% only:
Potassium chloride 20 mmol/L
Additional information
Potentially hazardous medication: may require special handling precautions, refer to RCH Safe Handling of Hazardous Medicines Procedure or relevant local guideline.
Observe closely for anaphylactic reactions.
Therapeutic Drug Monitoring required; refer to local guidelines.
Monitor blood pressure.
Use with caution in patients predisposed to QT interval prolongation or in patients being administered other medications known to prolong the QT interval.
Protect from light during storage.