Micafungin

Trade name

Mycamine

Presentation and preparation

Vial size (powder volume)	Fluid to add	Volume to add	Resulting concentration
50 mg (negligible)	Sodium chloride 0.9% OR Glucose 5%	5 mL	10 mg/mL
100 mg (negligible)	Sodium chloride 0.9% OR Glucose 5%	5 mL	20 mg/mL

Reconstitute with 5 mL of sodium chloride 0.9% or glucose 5%. Slowly add diluent towards the wall of the vial and gently rotate to wet the powder. Swirl gently to dissolve. Do not shake. Resulting solution must be diluted further prior to administration.

IV administration

Dilute to 0.5 to 1.5 mg/mL and infuse over 1 hour. Gently invert to mix. Do not shake.

Concentrations over 1.5 mg/mL must be infused via a central line to reduce risk of infusion reactions.

Maximum concentration if necessary: 4 mg/mL via a central line only.

Other routes of administration

IM: Not recommended.

SC: Not recommended.

Compatible IV fluids

Glucose 5%

Sodium chloride 0.9%

Micafungin 1 mg/mL or weaker:

Hartmann’s

Y-site only and Micafungin 1.5 mg/mL or weaker:

Glucose 10%

Potassium chloride 20 mmol/L

Additional information 

Protect from light during storage and administration. It is not necessary to protect tubing from light.