Intravenous fluid additive calculations to prepare 500 mL

* Note change in strength of concentrated sodium chloride; refer to previous editions or contact pharmacy if this strength is unavailable

The volumes below are calculated to allow for the average volume contained in 500 mL intravenous fluid bags. For fluid additive calculations of fluids differing from those listed below please contact the pharmacy department.
To prepare 500 mL
Fluid to be prepared Fluid bag (500 mL) Volume to withdraw before additions are made Additions
Glucose 50% Sodium chloride 23.4%
Glucose 5% and sodium chloride 0.9% Glucose 5% 30 mL – 20 mL
Glucose 5% and sodium chloride 0.45% Glucose 5% – – 10 mL
Glucose 5% and sodium chloride 0.225% Glucose 5% – – 5 mL
Glucose 10% and sodium chloride 0.9% Glucose 10% 30 mL – 20 mL
Glucose 10% and sodium chloride 0.45% Glucose 10% – – 10 mL
Glucose 10% and sodium chloride 0.225% Glucose 10% – – 5 mL
Glucose 12.5% Glucose 10% – 35 mL –
Glucose 12.5% and sodium chloride 0.9% Glucose 10% 70 mL 35 mL 20 mL
Glucose 12.5% and sodium chloride 0.45% Glucose 10% 70 mL 35 mL 10 mL
Glucose 12.5% and sodium chloride 0.225% Glucose 10% 70 mL 35 mL 5 mL
Glucose 15% Glucose 10% 50 mL 70 mL –
Glucose 15% and sodium chloride 0.9% Glucose 10% 100 mL 70 mL 20 mL
Glucose 15% and sodium chloride 0.45% Glucose 10% 80 mL 70 mL 10 mL
Glucose 15% and sodium chloride 0.225% Glucose 10% 80 mL 70 mL 5 mL
Glucose 20% Glucose 10% 120 mL 130 mL –
Glucose 20% and sodium chloride 0.45% Glucose 10% 140 mL 130 mL 10 mL
Glucose 20% and sodium chloride 0.225% Glucose 10% 140 mL 130 mL 5 mL