Note: This product is not licensed in Australia at the time of publication. The information in this monograph applies to the specified brand, formulation and strength only.
Also known as indomethacin.
Trade name
Ductaclose
Presentation and preparation
|
Vial size
(powder volume) |
Fluid to add
|
Volume to add
|
Resulting concentration
|
|---|---|---|---|
|
1 mg |
Water for injections |
1 mL 2mL |
1 mg/mL 0.5 mg/mL |
Reconstitute with 1 mL to provide a 1 mg/mL solution, or reconstitute with 2 mL to provide a 0.5 mg/mL solution.
IV administration
Give reconstituted solution undiluted over 20 – 30 minutes.
Other routes of administration
IM: Not recommended.
SC: Not recommended.
Compatible IV fluids
Y-site only:
Glucose 5%
Glucose 5% and sodium chloride 0.45%
Glucose 5% and sodium chloride 0.9%
Hartmann’s
Ringer’s
Sodium chloride 0.9%
Potassium chloride 20 mmol/L
Additional information
Extravasation risk.
Avoid IV infusion via an umbilical catheter into vessels near the superior mesenteric artery as this may reduce blood flow to the intestines and cause bowel ischaemia.
Use when facilities for cardiac monitoring exist.
Use immediately after reconstitution. Discard any unused vial contents.
Protect from light during storage.
Reconstituted solution should be clear, or slightly yellow.