Ganciclovir

Trade name

Cymevene, Ganciclovir (Lupin)

Presentation and preparation

Vial size (powder volume)	Fluid to add	Volume to add	Resulting concentration
500 mg (0.3 mL)	Water for injections	9.7 mL	50 mg/mL

IV administration

Dilute reconstituted solution to 10 mg/mL or weaker and give via a large peripheral vein over at least 1 hour.

Other routes of administration

IM: Contraindicated.

SC: Contraindicated.

Compatible IV fluids

Glucose 5%

Hartmann’s

Ringer’s

Sodium chloride 0.9%

Y-site only:

Potassium chloride 20 mmol/L

Additional information

Extravasation risk.

Cytotoxic medication: refer to RCH Safe Handling of Hazardous Medicines Procedure or relevant local guideline.

Therapeutic Drug Monitoring may be required; refer to local guidelines.

Ensure adequate hydration.