Filgrastim
Trade name
Nivestim, Zarzio
Presentation and preparation
Prefilled syringe:
120 microgram/0.2 mL
300 microgram/0.5 mL
480 microgram/0.5 mL
Remove prefilled syringe from refrigerator, allow to come to room temperature for 30 minutes before injecting.
IV administration
Dilute to a concentration of 15 microgram/mL or higher and give over at least 15 minutes. Concentrations less than 15 microgram/mL are unstable.
Can be administered as an intermittent or continuous infusion over 4 to 24 hours.
Do not shake.
Other routes of administration
IM: Not recommended.
SC: Suitable.
SC injection: Give undiluted. See local guidelines or Product Information for more details. Do not shake.
SC infusion: Dilute to a concentration of 15 microgram/mL or higher and give as a continuous SC infusion. Concentrations less than 15 microgram/mL are unstable.
Compatible IV fluids
Glucose 5%
Y-site only and filgrastim 15 to 30 microgram/mL:
Potassium chloride 20 mmol/L
Additional information
Do not administer within 24 hours prior to or 24 hours after chemotherapy.
Needle cover contains a latex derivative.
Refrigerate, do not freeze.
Protect from light during storage.
Zarzio: Solution should be clear and colourless or slightly yellow.