Trade name
Esomeprazole (AN), Esomperazole (Sun), Nexium
Presentation and preparation
|
Vial size
(powder volume) |
Fluid to add
|
Volume to add
|
Resulting concentration
|
|---|---|---|---|
| 40 mg (negligible) |
Sodium chloride 0.9% | 5 mL | 8 mg/mL |
Reconstitute with 5 mL of sodium chloride 0.9% for IV administration.
IV administration
Dilute to 0.4 to 0.8 mg/mL using sodium chloride 0.9% and give by intermittent infusion over 10 to 30 minutes.
Dilute to 0.8 mg/mL and give as a continuous infusion at a rate of 8 mg/hour.
Other routes of administration
IM: Not recommended.
SC: Not recommended. May be given as an intermittent or continuous SC infusion in palliative care settings.
Compatible IV fluids
Sodium chloride 0.9% is the preferred diluent.
Glucose 5%
Hartmann’s
Y-site only and esomeprazole 0.4 mg/mL or weaker:
Plasma-Lyte 148
Additional information
Observe closely for anaphylactic reactions.
Flush line with a compatible fluid before and after administration.
Discard vial contents after use.
Protect from light during storage.