Esmolol
Trade name
Brevibloc, Esmolol Hydrochloride Medsurge, Esmolol (Juno)
Strength
Premixed solutions are recommended for use in paediatrics.
10 mg/mL (volume: 10 mL)
IV administration
Give undiluted.
Loading doses are usually given over 1 to 2 minutes, followed by continuous infusion.
Administer preferably via a large peripheral vein or a central line.
RCH Standard Concentrations: 10 mg/mL
Other routes of administration
IM: Not recommended.
SC: Not recommended.
Compatible IV fluids
Glucose 5%
Glucose 5% and sodium chloride 0.9%
Glucose 5% and sodium chloride 0.45%
Hartmann’s
Sodium chloride 0.9%
Y-site and Brevibloc only:
Ringer’s
Plasma-Lyte 148
Potassium chloride 20 mmol/L
Additional information
Extravasation risk.
Use only when facilities for cardiac monitoring and cardio-respiratory resuscitation exist.
Taper the infusion slowly when discontinuing treatment; abrupt discontinuation may cause rebound effects.
Solution should be clear and colourless or slightly yellow.
Discard any unused vial contents.