Ephedrine

Trade name

Ephedrine hydrochloride:

Ephedrine-Hameln, Ephedrine Hydrochloride (Juno), Ephedrine (Interpharma)

Ephedrine sulfate:

DBL Ephedrine Sulfate

Presentation and preparation

Ephedrine hydrochloride:

  Ampoule:

  3 mg/mL (volume: 10 mL)

  30 mg/mL (volume: 1 mL)

  Prefilled syringe:

  30 mg/10 mL

Ephedrine hydrochloride 1 mg is equivalent to ephedrine 0.82 mg. 

Ephedrine sulfate:

  Ampoule:

  30 mg/mL (volume: 1 mL)

 Ephedrine sulfate 1 mg is equivalent to ephedrine 0.77 mg.

IV administration

Ephedrine hydrochloride:

Ephedrine Hydrochloride (Juno) and Ephedrine Interpharma only:

Give undiluted (3 mg/mL) as a slow IV injection.

Ephedrine-Hameln only:

Dilute to 3 mg/mL with sodium chloride 0.9% and give as a slow IV injection.

Ephedrine sulfate:

Dilute to 5 mg/mL with glucose 5% or sodium chloride 0.9% and give as a slow IV injection.

Other routes of administration

IM: Ephedrine sulfate only: Suitable.

SC: Ephedrine sulfate only: Suitable.

Compatible IV fluids

Hartmann’s

Sodium chloride 0.9%

Ephedrine-Hameln and DBL Ephedrine Sulfate only:

Glucose 5%

Glucose 10%

Y-site only and DBL Ephedrine Sulfate:

Plasma-Lyte 148

Additional information

Extravasation risk.

Use only when facilities for cardiac monitoring and cardio-respiratory resuscitation exist.

Protect from light during storage.