ciclosPORIN

Also known as cyclosporin, cyclosporine, ciclosporine

Trade name

Sandimmun

Strength

50 mg/mL (volume: 1 mL, 5 mL)

IV administration

Dilute to 0.5 to 2.5 mg/mL and give over 2 to 6 hours.

May also be given as a continuous infusion.

Non-PVC, DEHP-free bags and administration sets should be used.

RCH only: Refer to local protocol for storage and administration. 

Other routes of administration

IM: Not recommended.

SC: Not recommended.

Compatible IV fluids

Glucose 5%

Sodium chloride 0.9%

Y-site only and ciclosporin 2 mg/mL: 

Potassium chloride 20 mmol/L

Additional information

Observe closely for anaphylactic reactions.

Use only when facilities for cardiac monitoring and cardio-respiratory resuscitation exist. 

Monitor continuously for the first 30 minutes of the infusion, and frequently thereafter.

Potentially hazardous medication: may require special handling precautions; refer to RCH Safe handling of Hazardous Medicines Procedure or relevant local guideline. 

Therapeutic Drug Monitoring required; refer to local guidelines. Target levels vary according to the indication for use.

Solution should be a clear and slightly brown or yellow oil.

Protect from light during storage.