Trade name
Alfentanil (GH), Alfentanil (Medsurge), Rapifen
Strength
500 microgram/mL (volume: 2 mL, 10 mL)
IV administration
Dilute to 25 – 80 microgram/mL and give over 3 – 5 minutes or by continuous infusion.
Other routes of administration
IM: Not recommended.
SC: Not recommended. May be given as an intermittent or continuous SC infusion in palliative care settings.
Compatible IV fluids
Glucose 5%
Alfentanil 25 – 80 microgram/mL:
Glucose 5% and sodium chloride 0.9%
Hartmann’s
Sodium chloride 0.9%
Y-site only:
Potassium chloride 20 mmol/L
Additional information
For use in theatres or intensive care settings only.
Use only when facilities for cardiac monitoring and cardio-respiratory resuscitation exist.
Rapid infusion may cause chest wall rigidity and respiratory distress, especially in neonates. Monitor respiratory rate, sedation and blood pressure.
Concomitant use of CNS depressants (e.g. opioids, parenteral benzodiazepines, IM olanzapine) increases the risk of respiratory depression, sedation, coma and death.
Taper the infusion slowly when discontinuing treatment; abrupt discontinuation may cause withdrawal.
Protect from light during storage.