Adalimumab
Trade name
Amgevita*, Hadlima*, Humira, Hyrimoz*, Idacio*
*Amgevita, Hadlima, Hyrimoz and Idacio are biosimilar products of Humira
Presentation and Preparation
Prefilled syringe:
20 mg/0.2 mL*
20 mg/0.4 mL
40 mg/0.4 mL*
40 mg/0.8 mL
80 mg/0.8 mL*
Prefilled pen:
40 mg/0.4 mL*
40 mg/0.8 mL
80 mg/0.8 mL*
*Humira citrate-free formulations
IV administration
Not recommended.
Other routes of administration
IM: Not recommended.
SC: Suitable. Give undiluted.
Do not shake. Remove from refrigerator, allow to come to room temperature for 15 to 30 minutes before injecting. Do not remove cap or cover until administration.
Additional information
Observe closely for anaphylactic reactions.
Administration may cause injection site reactions, including pain, swelling erythema and itching.
Citrate-free Humira formulations may cause less injection site-related pain.
Amgevita pre-filled pen only: Needle covers contain latex.
Discard any unused syringe or pen contents.
Refrigerate, do not freeze.
Protect from light during storage.
Prefilled syringe/pen is stable if stored at room temperature for:
Amgevita, Humira, Idacio: 14 days.
Hyrimoz: 21 days.
Hadlima: 28 days.