Trade name

DBL Amikacin

Strength

250 mg/mL (volume: 2 mL)

IV administration

Dilute to 10 mg/mL or weaker and infuse over at least 30 minutes.

Infuse over 1 – 2 hours in neonates and infants.

Other routes of administration

IM: Suitable.

SC: Not recommended.

Compatible IV fluids

Glucose 5%

Glucose 5% and sodium chloride 0.45%

Glucose 5% and sodium chloride 0.9%

Glucose 10%

Sodium chloride 0.9%

Amikacin 5 mg/mL or weaker:

Hartmann’s

Ringer’s

Y-site only:

Plasma-Lyte 148

Potassium chloride 20 mmol/L

Additional information

Therapeutic Drug Monitoring required; refer to local guidelines.

IV aminoglycoside antibiotics are inactivated by IV cephalosporins, penicillins and teicoplanin; refer to Glossary and Notes